The Bionamic application

The Bionamic application is a web application accessed through the browser. All team members get access. See the screenshots page for examples.

Analysis

• No skills needed in programming or bioinformatics
• Visualization
• Analytics
• Statistics
• Bioinformatics
• Candidate selection

Data entry

• Import/export in various formats
• Assays
• Inventory
• Sequences
• CRO data

Track relations

• Every change is traceable to who, what and when
• Capture all relations between samples, molecules and assays
• From target to IND into CMC

Built for Collaboration

• Bionamic cloud is single source of truth
• A Git like system of commits and branches
• Check out old versions of the data
• Commit changes when they are ready
• Discard incorrect changes

Workflows and scripting

• User defined workflows
• Consistent naming of sequences
• Trace the origin of binders and antibodies
• Custom imports
• Automated cloning

Typical tasks made easy

• Align a VH-VL sequence to the ten most similar ones
• Find all isotypes a list of VH-VL sequences been cloned into
• Get all purification batches for a set of antibodies
• Assemble all relevant assays for a list of binders
• Calculate concentrations, biophysical properties and liabilities
• Analyse that dataset to select top candidates
• Generate antibodies and plasmids from VH-VL sequences and constant regions

Multispecific antibodies

• Design non-conventional antibodies
• Multiple binders per antibody
• Find corresponding assays and binders
• Trace the origins of mutated clones
• List the selection or immunization parameters